Scientists at the Lewis Katz School of Medicine have found a potential cure for patients infected with HIV.
Scientists at the Temple University school published a study in the Nature journal earlier this month showing that they can now effectively completely remove the virus from the DNA of human cells.
Medicalxpress.com reports:
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According to senior investigator on the new study, Kamel Khalili, PhD, Laura H. Carnell Professor and Chair of the Department of Neuroscience, Director of the Center for Neurovirology, and Director of the Comprehensive NeuroAIDS Center at the Lewis Katz School of Medicine at Temple University (LKSOM), “Antiretroviral drugs are very good at controlling HIV infection. But patients on antiretroviral therapy who stop taking the drugs suffer a rapid rebound in HIV replication.” The presence of numerous copies of HIV weakens the immune system and eventually causes acquired immune deficiency syndrome, or AIDS.
Curing HIV/AIDS—which has claimed the lives of more than 25 million people since it was first discovered in the 1980s – is the ultimate goal in HIV research. But eliminating the virus after it has become integrated into CD4+ T-cells, the cells primarily infected with HIV, has proven difficult. Recent attempts have focused on intentionally reactivating HIV, aiming to stimulate a robust immune response capable of eradicating the virus from infected cells. However, to date, none of these “shock and kill” approaches has been successful.
Dr. Khalili and colleagues decided to try a different approach, specifically targeting HIV-1 proviral DNA (the integrated viral genome) using uniquely tailored gene editing technology. Their system includes a guide RNA that specifically locates HIV-1 DNA in the T-cell genome, and a nuclease enzyme, which cuts the strands of T-cell DNA. Once the nuclease has edited out the HIV-1 DNA sequence, the loose ends of the genome are reunited by the cell’s own DNA repair machinery.
In previous work, Dr. Khalili’s team had demonstrated the ability of their technology to snip out HIV-1 DNA from human cell lines. In their latest study, however, they concentrated on latently and productively infected CD4+ T cells to show not only that the technology eliminates the virus from cells but also that its persistent presence in HIV-1-eradicated cells actually protects them against reinfection. More importantly, they carried their work over to ex vivo experiments, in which T-cells from patients infected with HIV were grown in cell culture, showing that treatment with the gene editing system can suppress viral replication and dramatically reduce viral load in patient cells.
In another major component of the study, Dr. Khalili’s team addressed questions about off-target effects and toxicity. Using an approach known as ultra-deep whole-genome sequencing, which is considered the gold standard for genomic assessment, the researchers analyzed the genomes of HIV-1-eradicated cells for mutations in genes outside the region targeted by the guide RNA. Their analyses ruled out off-target effects on genes, including potential collateral effects on cellular gene expression. Studies of cell viability and proliferation showed that HIV-1-eradicated cells were growing and functioning normally.
“The findings are important on multiple levels,” Dr. Khalili said. “They demonstrate the effectiveness of our gene editing system in eliminating HIV from the DNA of CD4 T-cells and, by introducing mutations into the viral genome, permanently inactivating its replication. Further, they show that the system can protect cells from reinfection and that the technology is safe for the cells, with no toxic effects.”
“These experiments had not been performed previously to this extent,” he added. “But the questions they address are critical, and the results allow us to move ahead with this technology.”
Sean Adl-Tabatabai
hello to all viewers my name is Rebeca Lizzy i am 27years old i am
married to late Mr Richard Watt i am from UK Baltimore to be precise i
have two children, my late husband infected me with HIV disease before
he died,i spent so much money buying drugs from hospitals hope that i
will be cured , still all was in vain .i contacted so many herbal
doctors,which they indeed tried there best but was unable to provide for
me a possible cure, luckily a good friend of mine told me about a great
herbal , Dr egba, she introduce me to Dr egba i had no choice but to
comply with what Dr egba was to offer because i really want this disease
fast gone from my system, so i did all what Dr egba said and he
eventually prove to me that he is really powerful, Dr egba i am really
grateful to you, for all the help and good time i worked with you thanks
Dr egba for making my life better today. contact him on this email
dregbasolutiontemple@gmail.com or call on +2348107085403
I can’t believe this. A great testimony that i must share to all HIV patient in the world i never believed that their could be any complete cure for HIV or any cure for HIV,i saw people’s testimony on blog sites of how DR AIGBI prepare herbal medication and brought them back to life again. i had to try it too and you can,t believe that in just few weeks i started using it all my pains stop gradually and i had to leave without the drugs the doctor gave to me. Right now i can tell you that few months now i have not had any pain, and i have just went for text last week and the doctor confirmed that there is no trace of any HIV in my body. Glory be to God for leading me to this genuine to DR AIGBI I am so happy as i am sharing this testimony. My advice to you all who thinks that their is no complete cure for HIV VIRUS that is Not true ,just contact him and get cure from DR AIGBI for your HIV and you will be free and free forever, Try it and you will not regret it because it truly works. One thing i have come to realize is that you never know how true it is until you try. Remember, delay in treatment leads to death. Here is his email:draigbiherbalhome@gmail.com or whatsapp him on +2348105867388
hello every one my name is Messi Rose i am from los Angele Caliornia, i have been suffering from HIV disease for the last Three years. During the first year, I had faith in God that i would be healed someday.This disease started circulating all over my body and i have been taking treatment from my doctor, few weeks ago i was searching on the internet if i could get any information concerning the prevention of this disease, on my search i saw a testimony of someone who has been healed from HIV Disease by this Man DR Osas and she also gave the email address of this man and advise we should contact him for any sickness that he would be of help, so i wrote to DR osas telling him about my HIV he told me not to worry that i was going to be cured!! hmm i never believed it,, well after all the procedures and remedy given to me by this man few weeks later i started experiencing changes all over me as the Dr Osas Assured me that i have cured, after some time i went to my doctor to confirmed if i have be finally healed behold it was TRUE So friends my advise is if you have such sickness or any other at all you can email DR Osas on drosasspelltemple@gmail.com. I am indeed grateful for the help, i will forever recommend you to my friends.
Good day everyone my name is Nora, I have this great opportunity to share this testimony about how I get cure for my HIV,Two years ago I was HIV positive so I was suffering from it I was doing one thing or the order to get a cure there was know way for it so I was on my research on the internet I saw a testimony of a young man, about how DR. Ozala help him get a cured for HIV with his herbal medicine I was surprise and I do not believe I said okay let me try him I contact him that night on his email and he gave me instructions and I follow it he told me what to do and I did it, after a week he sent to me the medicine true DHL he told me how to use it and I did exactly how he instructed me to use it, after two weeks he told me that I should go for test, indeed I did it, and behold I was HIV “negative” am so grateful Doctor, now am happy with my Husband and two kids I want to use this opportunity to say this, please if you have this kind of disease called HIV, I want you to contact him on is email;drozalahomeremedy@gmail.com or whatsapp him +2347064614569 or my assistant call me +2347064614569 and my email: drozalahomeremedy@gmail.com and he can also help you get a cure for HPV, HERPES, CANCER,disease and he can cure you from any kind of diseases with his herbal medicine. all you have to do is to believe him. thank you my Dr may god bless you……
E-mail: drozalahomeremedy@gmail.com or whatsapp: +2347064614569
My name is Helen from UK i am so very happy to testify about this great spiritual healer Dr.onoja that help me cured my HIV disease. I have been suffering from this HIV disease for over 5 years and i have found no cure, on till this blessed day i was browsing through the internet and i saw a woman testifying about this great powerful spiritual healer Dr.onoja who helped her cured her HIV disease with a herbal cure. And also i contacted him Dr.Sam and i explain all my problem to him and he told me that i should not worry that he is going to help me prepare a herbal medicine for me and after that, he told me that he will send me the herbal medicine that i will use in curing my HIV disease and on the herbal medicine there are some rules that i will follow in using the herbal medicine, and i stood by it, and after using the herbal medicine i felt changing in me and i went for medical check up and the doctor told me that i am cured from the HIV disease and i was so very happy now that i am free from HIV disease and also the woman mentioned that Dr.onoja can also cure this deadly diseases called Cancer, Diabetes, Syphilis, Herpes, i am now saying that anyone who is suffering from any of this deadly disease should contact this powerful great spiritual healer with this onojaosuba@yahoo.com or dr.onojaspelltemple@gmail.com
my name is binaley salami, am from California actually i was suffering form HIV for over 5 years now and i have gone to so many doctors for help they can a solution to my problem, thing the day i met this man of powerful Dr Onoja in net he prayed for me and ask me to do so many thing off wish i did. golly be to gods for his messy and his grease that healed me. i am so happy to give ma life to god. if u need and assistance if any thing do contact this powerful Dr, Dr. onoja dr.onojaspelltemple@gmail.com
need the most powerful Dr Onoja have ever experienced in life. I Am Posting this to the Forum in case there is anyone who has similar problem and still looking for a way out,
(1) To care HIV/AID or related illness
(2) Bring back lost lover, even if lost for a long time
(3) you need a divorce in your relationship
(4) You want to be promoted in your office.
(5) You want women & amp; men to run after you.
(6) If you want a child.
(7) You want to be rich.
(8) You want to tie your husband & wife to be yours forever.
(9) If you need financial assistance.
(10) Herbal care
(11)If you want your ex back
should contact dr.onojaspelltemple@gmail.com or+8142559061
It still unbelievable to believe that HIV AIDS still has cure, me and my Husband has been suffering from HIV AIDS for so many years and we have search for help but we were unable to find one, i was told that there was no cure for HIV AIDS but somehow i believe that there was someone out that has a cure, so that was how i went in search for s solution on how to get cured of HIV AIDS and surprisingly i saw comment on daily news papers where lady testify of how Dr OMO herbal medicine cure her, i was so confused because first i thought that there was no cure but now seeing that someone outside has a cure, i thoughts of it as a scam but something told me to give it a try and when i did he reply me and assure me that me and my husband will be cured once we receive his herbal medicine, that was how he prepared it, and send my herbal medication that me and my husband used that cure me and my husband in Just 2 weeks and we were tested HIV AIDS Negative. All Thanks to the powerful Dr OMO for his help in my life. contact him on his email FREEHIVCUREHOME@GMAIL.COM
whatssup him on +2348077309081.
Am from COLORADO my name is Linda Adalms The last thing I will ever do is to believe on MEDICAL drugs intense of hiv aids for years now I being suffering for that virus, I so much believe on my doctor, he assure me that the American scientist have discover a cure call “VACCINE” that can cure my hiv aids I go for the purchase use as they instructed still I remain hiv positive.on August 27 2016 while searching on Google i typed I NEED A CURE FOR HIV/AIDS I read many testimony about doctor Taiye how he cure a man who was hiv aids for 13 years I decide to email him first, he told me everything about doctor taiye how he cured his hiv aids with full assurance them I went his way and contact dr Akula at: sangohealingtemple@gmail.com he told me not to worry and ask for my details which I send, him them told me that I will be fine them he assure me that within the next three day if I can follow his procedure I will get my cure. i followed as him instructed. As am giving this testimony am now hiv/aids negative with the help of dr. Akula, if you have such virus do yourself a favor and contact doctor Akula on his emai: sangohealingtemple@gmail.com or contact me at Lindaadalms@yahoo.com
I THOUGHT THE PYSICIANS SAY NO CURE FOR HIV/AIDS?, I AM TELLING YOU TODAY THAT DR OKEKE CURE HIV/AIDS
WITH HIS HERBAL MEDICINE AND ONCE YOU GET CURED YOU ARE FOREVER CURED IT IS NEVER REVERSABLE.
MY NAME IS LEOPOLDO FROM UNITED KINGDOM,I AM USING THIS GREAT OPORTUNITY TO SAVE LIFE
BY SHARING MY TESTIMONY THAT THERE IS A CURE FOR HIV/AIDS BECAUSE I AM A LIVING TESTIMONY,I SUFFERED
FOR HIV/AIDS FOR GOOD 1YEAR AND 2MONTHS AFTER LOOSING HOPE THAT I CAN NEVER GET THE CURE BEACAUSE THE DOCTORS SAID
THERE IS NO CURE FOR IT,BUT THANKS BEEN TO THIS GREAT MAN CALLED DR OKEKE WHOM I READ A TESTIMONY ABOUT ON HOW HE CURED HIV/AIDS WITH HIS HERBAL MEDICINE,I NEVER BELIEVE THIS BUT I DECIDED TO CONTACT HIM THROUGH THE STATED EMAIL,okekespiritualhealinghome@gmail.com and he send to me a herbal medicine and ask me to drink and bath with the herbal medicine for one month but to my greatest surprises, i went for a medical test after two weeks and my status was negetive till today i cant keep sharing this testimony please brothers and sisters there is a cure to hiv/aids, contact this man for what ever you are going through, what ever sickness you are suffering from, hiv/aids,perkinsons disease, ALS,CANCERS,HERPES. contact him with his email via, okekespiritualhealinghome@gmail.com
Are you in need of help to solve your infertility problem or to get
pregnant? He can also cure disease like Cancer, Diabeties, Herpes, Hepatitis B, Etc. You can reach me on email: maquillagemmaprotacio@gmail.com
I am here to testify about Dr Obose Herbal Medicine. My name is Pauline Abela. I am happy to inform the general public on how i was cured of GENITAL HERPES by Dr Obose Natural Medicine. I visited different hospital but they gave me prescription of drugs such as Zovirax, Valtrex, and Famvir, these drugs are very expensive and after everything they did not even work. Then my friend directed me to Dr Obose Natural Herbal Medicine, saying Dr Obose has cure to all kind of deadly disease and his contact details was shown there Email: dr.oboseherbalhome@gmail.com… I contacted him and he sent his Herbal medicine to me which i took and it seriously worked for me. Am a free person now without Herpes virus. I pray for you Dr Obose. While i was talking to him i understood he can also cure Hiv, Cancer, help to solve pregnancy problem and also restore broken relationship and many more. contact him with his information was shown there Email: dr.oboseherbalhome@gmail.com
My name is Kate mark, i want to tell the world about how i got cured from HIV Disease by Dr. Ozala. i was Infected with HIV Disease for so many years and i was tired of life because of the sufferings i was going through, so one faithful day a friend of mine gave me a contact of a herbal doctor who cured her cousin from HIV Disease and immediately i contacted the Doctor on his email address: (drozalahomeremedy@gmail.com) and his whatsapp: +2349074008745, and immediately the Doctor sent me a herbal medicine and told me to take the medicine only at bed time with is at night and i did and immediately the HIV Virus DISAPPEARED and i was cured from HIV Disease, the name of this Doctor is Dr Ozala.. so if you are infected with HIV Disease or any other dangerous and uncurable Disease then Dr. Ozala is the right man to be contacted for the cure. so kindly contact him now on his email: (drozalahomeremedy@gmail.com) or His Whatsapp number: +2349074008745… once again, Dr. Ozala thank you very much for what you did for me am very grateful… He can also cure Hepatitis Virus,
Get a cure for HIV is a powerful concept, often spoken of as HOLY GRAIL of HIV research. AIthough effective anti-HIV drugs have transformed HIV into a chronic manageable conditions – a condition you live rather than die from – taking life -long therapy is a very different proposition to being definitively cured. i put it to the whole human race that there is an affordable , scalable HIV cure that worked as well as would put the global eradication of new HIV infections within reach, while also transforming the lives of those now living with the virus. given the effectiveness of this drugs in both treating and preventing HIV infection, i will say to everyone reading this , that i am a living witness to it. unlike fraudster and online scammers who will play you and leave you frustrated with lose of money and hope, this drugs cost less and it is worth a try. if you are intersted in getting cured of your own illeness, Below is the communication link of the doctor who has the new medicine which i took that got me cure. Dr Usman Uwaifo Rabiu E-mail;(usmanuwaiforabiu@gmail.com). call or whatsapp him on +234 815 464 1673. BEWARE OF FRAUDSTERS ONLINE.
I am so happy to write this few words of mine about the great Doctor who has brought me out out from the pit of shame and death. If not for him! where would have I run to. I have been HIV Positive for the past five years now and I have done everything I have been told to do to get a cure but nothing was working out until one faithful day I decided to share my problem out with a friend of mine on Facebook because it says “A problem share has a solution” and “An Idleness kills someone who always keep things to him/herself”. I explained everything to her and she told me about one of the top 10 listed greatest and powerful doctor in Africa called Doctor Ayes who has helped her husband in getting cured from COPD and Herpes. He gave me the doctor email UNSTOPABLESHRINE@GMAIL.COM AND UNSTOPABLESHRINE@OUTLOOK.COM and Phone number of Doctor. I contacted him and he told me everything about his work and medicines and procedures how to get them and use it. This was the fifth time I have contacted doctor’s online but this particular one called Doctor Ayes was extremely different, I tried all I could to meet up with his demand and after three days the medicine gets to me and I use it for three weeks only according to his command and instructions and called my doctor for check up was so surprise to find myself negative and I couldn’t believe him and decided to went to three different hospitals and same result came out “Negative” I am saying this mainly because of those who has loose hopes in life not to loose hope and faith contact Dr. Ayes on his email (UNSTOPABLESHRINE@GMAIL.COM AND UNSTOPABLESHRINE@OUTLOOK.COM) today and he will change your life miraculously…
Wish you all the best you wish yourself and thanks for taking your time for reading this great testimony of mine
Happy New Year to you all
i’m a renowned professional herbalist that deals in the production of various herbal medicines, which can cure various deadly sexually transmitted diseases (STD’s), in the likes of gonorrhea chlamydia, genital herpes, herpes simplex virus syphilis, HPV, HIV/AIDS, trichomoniasis and so on, and other diseases such as cancer, fibroid fever, acute hepatitis, hepatitis A, B, and C, menstrual problems, asthma, pile, appendices, kidney problem, heart failure low sperm count, arthritis, and the likes of many other diseases. i’ve been able to use natural roots and herbs to restore health and put smile on the faces of patients i”m making an awareness to everyone that there is hope and cure for that health problem you are facing…You can contact me through this email(rabiuhamadu@gmail.com)
WHATSAPP:(+347536719427)
hello friends,
my name is julissa rodrigo,i single mom of 3 children.am here to testify how Dr.Rabiu cure my 6years Hiv/Aids with his Herbal medicine.at first when a friend of mine introduce me to the herbal doctor i never believed her because of fake and scammer, but i have to give a taught to it then i contacted the Doctor through his email: rabiuhamadu@gmail.com, and he sent me the herbs and instruction on how to take it.after 2weeks i went back for checkup and i was confirmed HIV negative
I am so happy to write this few words of mine about the great Doctor who has brought me out out from the pit of shame and death. If not for him! where would have I run to. I have been HIV Positive for the past five years now and I have done everything I have been told to do to get a cure but nothing was working out until one faithful day I decided to share my problem out with a friend of mine on Facebook because it says “A problem share has a solution” and “An Idleness kills someone who always keep things to him/herself”. I explained everything to her and she told me about one of the top 10 listed greatest and powerful doctor in Africa called Doctor Ayes who has helped her husband in getting cured from COPD and Herpes. He gave me the doctor email UNSTOPABLESHRINE@GMAIL.COM AND UNSTOPABLESHRINE@OUTLOOK.COM and Phone number of Doctor. I contacted him and he told me everything about his work and medicines and procedures how to get them and use it. This was the fifth time I have contacted doctor’s online but this particular one called Doctor Ayes was extremely different, I tried all I could to meet up with his demand and after three days the medicine gets to me and I use it for three weeks only according to his command and instructions and called my doctor for check up was so surprise to find myself negative and I couldn’t believe him and decided to went to three different hospitals and same result came out “Negative” I am saying this mainly because of those who has loose hopes in life not to loose hope and faith contact Dr. Ayes on his email (UNSTOPABLESHRINE@GMAIL.COM AND UNSTOPABLESHRINE@OUTLOOK.COM) today and he will change your life miraculously…
Wish you all the best you wish yourself and thanks for taking your time for reading this great testimony of mine
Happy New Year to you all…
scam you out of your money and no cure