WHO Warns That New Covid Variant Called ‘Mu’ May Be More Vaccine Resistant

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Covid MU strain WHO

The World Health Organisation (WHO) is warning that a new coronavirus variant named Mu could be more resistant to vaccines.

B.1.621 better knows as Mu, was first identified in Colombia in January and outbreaks of cases have been recorded in South America and Europe.

The WHO has designated Mu a variant of interest and say they are closely monitoring the strain.

In July this year Public Health England (PHE) also declared that they had the Mu variant under investigation.

The Hindu reports: The cases of the Mu variant have also been reported in the U.K., Europe, the U.S. and Hong Kong.

The new ‘variant of interest’ is being closely monitored, the U.N. health agency said.

Although the global prevalence of the Mu variant among sequenced COVID-19 cases is currently below 0.1%, its prevalence in Colombia (39%) and Ecuador (13%) has consistently increased, it said.

The new variant was added to the WHO’s watchlist on August 30 after it was detected in 39 countries and found to possess a “constellation of mutations that indicate potential properties of immune escape,” it said.

Reports on the variant’s prevalence should be “interpreted with due consideration” given the low sequencing capacity of most countries, the U.N. agency said.

Mu is the fifth variant of interest to be monitored by the WHO since March. It has a number of mutations that suggest it could be more resistant to vaccines, the WHO warned, but said that further research would be needed to confirm this.

The preliminary data shows it may evade immune defences in a similar way to the Beta variant first discovered in South Africa, the UN agency said, adding that this needs to be confirmed by further work.

“More studies are required to understand the phenotypic and clinical characteristics of this variant,” it said, adding that the epidemiology of the Mu variant in South America, particularly with the co-circulation of the Delta variant, will be monitored for changes.

As of August 29, over 4,500 sequences (3,794 B.1.621 sequences and 856 B.1.621.1 sequences), genome sequences, analysed samples of the virus taken from patients, have been designated as Mu in the past four weeks. The sequences are used to track how it moves through the population, on an open-source genome repository, known as GISAID.

Most of these have been reported in the U.S (2,065) and Colombia (852), Mexico (357) and Spain (473).

Meanwhile, South African scientists are closely monitoring the development of another new variant there.

Niamh Harris
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